Lilly, Novo Nordisk near White House deals on obesity drug prices, Endpoints News reports

North America
Source: ReutersPublished: 11/04/2025, 11:45:02 EST
Eli Lilly
Novo Nordisk
Obesity Drugs
Drug Pricing
Medicare
Trump Administration
A patient injects herself with her weekly dose of Wegovy in New Columbia, Pennsylvania, U.S., November 13, 2023. REUTERS/Hannah Beier/File Photo Purchase Licensing Rights, opens new tab

News Summary

Eli Lilly and Novo Nordisk are reportedly close to striking a deal with the White House on drug pricing for their weight loss medicines, in exchange for Medicare coverage of their products, according to Endpoints News. Under the proposed agreement, the companies would offer the lowest dose of their respective obesity drugs at $149 per month, sources familiar with the matter told Endpoints News. The announcement of this deal could come as early as this week. This initiative aligns with President Trump's ongoing pressure on drugmakers to lower U.S. prescription drug prices to levels comparable with other developed nations. In return, the inclusion of these drugs under Medicare—a federal health insurance program—would unlock a significant new reimbursement market for both pharmaceutical giants. Pfizer previously reached a similar agreement with the Trump administration in September, committing to reduce prescription drug prices in the Medicaid program in return for tariff relief.

Background

U.S. drug prices have historically been higher than in other developed nations, a persistent point of contention in American politics and for consumers. Following his re-election in 2024, President Trump continues to prioritize lowering prescription drug costs as a key agenda item for his administration. The obesity drug market, particularly for GLP-1 agonists like Lilly's Zepbound and Novo Nordisk's Wegovy, is experiencing explosive growth, but high monthly costs have limited accessibility. Medicare, the federal health insurance program for individuals aged 65 and older or those with disabilities, typically does not cover weight loss medications, making these negotiations a significant shift in policy.

In-Depth AI Insights

What are the deeper strategic intentions behind the Trump administration's drug pricing strategy? - Ostensibly aimed at reducing patient costs and fulfilling campaign promises, this approach is more profoundly a "carrot and stick" strategy to reshape the U.S. pharmaceutical pricing model. By offering access to large markets like Medicare as leverage, the administration can bypass traditional legislative stalemates and negotiate directly with drugmakers, effectively achieving price reductions without outright price controls. - It may also aim to bolster the U.S. pharmaceutical industry's bargaining power by establishing a "most-favored-nation" pricing principle to secure the lowest global prices for American patients, while potentially using tools like tariff relief to offset drugmakers' potential profit losses, thereby preventing a significant industry exodus. What are the long-term implications of this deal for Lilly's and Novo Nordisk's profitability and market positioning? - While potentially facing immediate margin pressure, gaining Medicare coverage will unlock a massive and largely untapped market for both companies. The inclusion of obesity drugs in Medicare will significantly expand their patient base, particularly among the price-sensitive elderly population. This could lead to larger sales volumes and more stable revenue streams in the long run, offsetting per-unit price reductions. - Furthermore, being pioneers in striking a deal with the government may grant them a first-mover advantage and stronger government relations within an evolving regulatory landscape, which is crucial in the highly regulated pharmaceutical sector. Other drugmakers may face greater future pressure to reduce prices without necessarily securing equivalent market access conditions. How will the evolving U.S. drug pricing model impact the broader biopharmaceutical investment landscape? - The normalization of this "government-drugmaker direct negotiation" model implies that future drug launch pricing strategies will become more complex and uncertain. Pharmaceutical companies will need to factor policy risks and potential pricing pressures into their R&D decisions much earlier. - The investment return model for innovative drugs may be reshaped. Drugs with unique, indispensable efficacy and demonstrable long-term cost-effectiveness may still command premium pricing, while those with intense competition or marginal therapeutic differences will face greater downward price pressure. This could push the industry to focus more on truly disruptive innovations rather than "me-too" drugs.