Ozempic maker Novo Nordisk ousts CEO amid plunging share price as rival Eli Lilly gains market share

Global
Source: New York PostPublished: 05/16/2025, 12:29:34 EDT
Novo Nordisk
Eli Lilly
Weight-Loss Drugs
Pharmaceuticals
Market Competition
Lars Fruergaard Jorgensen had led Denmark’s Novo since 2017. Ritzau Scanpix/AFP via Getty Images

News Summary

Danish pharmaceutical company Novo Nordisk ousted CEO Lars Fruergaard Jorgensen on Friday over concerns the company is losing its first-mover advantage in the highly competitive obesity drug market. The move came days after the company cut its sales and profit forecast for the first time in over four years. Despite Jorgensen's prediction of a return to growth in the US market in the second half, Novo's shares have plunged since hitting a peak last year, partly due to increased competition, particularly from Eli Lilly, and an unimpressive pipeline. Eli Lilly's Zepbound has surpassed Wegovy in US prescriptions since mid-March. Novo Nordisk's shares fell on the news of the CEO change and are down 32% year-to-date and 59% from their peak last year. Some analysts and investors expressed surprise and confusion over the decision to remove Jorgensen, citing his eight successful years leading the company. Novo's chairman sought to reassure the market that the company's strategy remains intact but acknowledged the change was made in light of recent market challenges and share price performance. The Novo Nordisk Foundation controls 77% of the voting shares through its investment arm.

Background

Novo Nordisk is a Danish pharmaceutical giant known for its diabetes and obesity treatments. In recent years, its weight-loss drugs Wegovy and Ozempic have seen skyrocketing sales, making it Europe's most valuable listed company. However, the obesity drug market is becoming increasingly competitive, with US rival Eli Lilly making inroads into Novo Nordisk's market share with drugs like Zepbound.

In-Depth AI Insights

What are the real drivers behind ousting a successful CEO? - While the press release and chairman cited market challenges and share price decline, these may be surface-level reasons. - The true drivers likely stem from deeper concerns about the future competitive landscape, particularly Eli Lilly's rapid rise with Zepbound and its potential for long-term erosion of Wegovy's market share. - The Foundation, as the controlling shareholder, may have grown dissatisfied with management's ability to effectively counter competitive pressure and bolster the pipeline, especially after the company's valuation nearly halved. - The CEO removal could be an aggressive signal that the company needs a more disruptive new strategy or leadership to regain market initiative, rather than merely stating the strategy is unchanged. What does this change imply for the future competitive dynamic between Novo Nordisk and Eli Lilly? - Novo Nordisk's CEO change may signal a move towards more aggressive market tactics or R&D focus shifts aimed at re-establishing leadership. - Eli Lilly's success with Zepbound demonstrates strong execution. With new leadership at Novo, the competition between the two companies could broaden beyond products and sales to wider corporate strategy. - Investors will be closely watching the new CEO's background and the specific changes they bring, which will directly impact future growth expectations and market share for both companies. What are the broader implications for the weight-loss drug market and biotech investment? - Even companies with seemingly strong first-mover advantages and market dominance face risks from rapid change and intense competition. - The importance of the R&D pipeline is re-emphasized; failure to consistently deliver competitive new products is a key factor in declining market share and valuation. - Investors need to re-evaluate the depth of the moat for high-growth biotech companies and be wary of the "winner-take-all" narrative being disrupted by fast-moving market entrants.